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Synthesis of Difluoroarymethyl-Substituted Benzimidazo[2,1-a]isoquinolin-6(5H)-ones under Mild Conditions

[Image: see text] A highly efficient method for synthesis of difluoroarymethyl-substituted benzimidazo[2,1-a]isoquinolin-6(5H)-ones using 2-arylbenzoimidazoles with α,α-difluorophenylacetic acid as reaction substrates has been developed through radical cascade cyclization. The advantage of this stra...

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Detalles Bibliográficos
Autores principales: Sui, Kaixia, Leng, Yuting, Wu, Yangjie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9979369/
https://www.ncbi.nlm.nih.gov/pubmed/36872989
http://dx.doi.org/10.1021/acsomega.2c06689