Nesfatin-1 suppresses autophagy of chondrocytes in osteoarthritis via remodeling of cytoskeleton and inhibiting RhoA/ROCK signal pathway

Autophagy and cytoskeleton integrity of chondrocytes are a considered as major factors in the progression of osteoarthritis (OA) involving excessive chondrocyte apoptosis and senescence. Nesfatin-1, an adipokine, has been reported to be closely related to cell autophagy and cytoskeleton malfunction....

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Detalles Bibliográficos
Autores principales: Jiang, Lifeng, Moqbel, Safwat Adel Abdo, Zhu, Junxiong, Fu, Qiangchang, Lai, Jiabin, Lin, Changjian, Wu, Lidong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9979404/
https://www.ncbi.nlm.nih.gov/pubmed/36859270
http://dx.doi.org/10.1186/s13018-023-03539-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9979404/
https://www.ncbi.nlm.nih.gov/pubmed/36859270
http://dx.doi.org/10.1186/s13018-023-03539-5

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