Irinotecan-gut microbiota interactions and the capability of probiotics to mitigate Irinotecan-associated toxicity

BACKGROUND: Irinotecan is a chemotherapeutic agent used to treat a variety of tumors, including colorectal cancer (CRC). In the intestine, it is transformed into SN-38 by gut microbial enzymes, which is responsible for its toxicity during excretion. OBJECTIVE: Our study highlights the impact of Irin...

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Detalles Bibliográficos
Autores principales: Mahdy, Marwa S., Azmy, Ahmed F., Dishisha, Tarek, Mohamed, Wafaa R., Ahmed, Kawkab A., Hassan, Ahmed, Aidy, Sahar El, El-Gendy, Ahmed O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9979425/
https://www.ncbi.nlm.nih.gov/pubmed/36864380
http://dx.doi.org/10.1186/s12866-023-02791-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9979425/
https://www.ncbi.nlm.nih.gov/pubmed/36864380
http://dx.doi.org/10.1186/s12866-023-02791-3

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