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PI3K pathway mutation predicts an activated immune microenvironment and better immunotherapeutic efficacy in head and neck squamous cell carcinoma

BACKGROUND: PI3K pathway is the most frequently mutated pathway in head and neck squamous cell carcinoma (HNSC), which plays a crucial role in tumorigenesis and progression. In the present study, we aimed to investigate the role of PI3K pathway mutation in clinical prognosis prediction and the relat...

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Detalles Bibliográficos
Autores principales: Wang, Libo, Chen, Kejun, Weng, Siyuan, Xu, Hui, Ren, Yuqing, Cheng, Quan, Luo, Peng, Zhang, Jian, Liu, Zaoqu, Han, Xinwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9979448/
https://www.ncbi.nlm.nih.gov/pubmed/36864522
http://dx.doi.org/10.1186/s12957-023-02938-6