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CD39/CD73/A2AR pathway and cancer immunotherapy

Cancer development is closely associated with immunosuppressive tumor microenvironment (TME) that attenuates antitumor immune responses and promotes tumor cell immunologic escape. The sequential conversion of extracellular ATP into adenosine by two important cell-surface ectonucleosidases CD39 and C...

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Detalles Bibliográficos
Autores principales: Xia, Chenglai, Yin, Shuanghong, To, Kenneth K. W., Fu, Liwu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9979453/
https://www.ncbi.nlm.nih.gov/pubmed/36859386
http://dx.doi.org/10.1186/s12943-023-01733-x