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CD39/CD73/A2AR pathway and cancer immunotherapy
Cancer development is closely associated with immunosuppressive tumor microenvironment (TME) that attenuates antitumor immune responses and promotes tumor cell immunologic escape. The sequential conversion of extracellular ATP into adenosine by two important cell-surface ectonucleosidases CD39 and C...
Autores principales: | Xia, Chenglai, Yin, Shuanghong, To, Kenneth K. W., Fu, Liwu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9979453/ https://www.ncbi.nlm.nih.gov/pubmed/36859386 http://dx.doi.org/10.1186/s12943-023-01733-x |
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