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Machine learning identification of thresholds to discriminate osteoarthritis and rheumatoid arthritis synovial inflammation

BACKGROUND: We sought to identify features that distinguish osteoarthritis (OA) and rheumatoid arthritis (RA) hematoxylin and eosin (H&E)-stained synovial tissue samples. METHODS: We compared fourteen pathologist-scored histology features and computer vision-quantified cell density (147 OA and 6...

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Detalles Bibliográficos
Autores principales: Mehta, Bella, Goodman, Susan, DiCarlo, Edward, Jannat-Khah, Deanna, Gibbons, J. Alex B., Otero, Miguel, Donlin, Laura, Pannellini, Tania, Robinson, William H., Sculco, Peter, Figgie, Mark, Rodriguez, Jose, Kirschmann, Jessica M., Thompson, James, Slater, David, Frezza, Damon, Xu, Zhenxing, Wang, Fei, Orange, Dana E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9979511/
https://www.ncbi.nlm.nih.gov/pubmed/36864474
http://dx.doi.org/10.1186/s13075-023-03008-8