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EBS-seq: enrichment-based method for accurate analysis of 5-hydroxymethylcytosine at single-base resolution

BACKGROUND: A growing body of research has emphasized 5-hydroxymethylcytosine (5hmC) as an important epigenetic mark. High-resolution methods to detect 5hmC require high sequencing depth and are therefore expensive. Many studies have used enrichment-based methods to detect 5hmC; however, conventiona...

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Detalles Bibliográficos
Autores principales: Lee, Jaywon, Lee, Dongin, Kim, Hwang-Phill, Kim, Tae-You, Bang, Duhee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9979530/
https://www.ncbi.nlm.nih.gov/pubmed/36859282
http://dx.doi.org/10.1186/s13148-023-01451-7