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EBS-seq: enrichment-based method for accurate analysis of 5-hydroxymethylcytosine at single-base resolution
BACKGROUND: A growing body of research has emphasized 5-hydroxymethylcytosine (5hmC) as an important epigenetic mark. High-resolution methods to detect 5hmC require high sequencing depth and are therefore expensive. Many studies have used enrichment-based methods to detect 5hmC; however, conventiona...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9979530/ https://www.ncbi.nlm.nih.gov/pubmed/36859282 http://dx.doi.org/10.1186/s13148-023-01451-7 |