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Discovery of 2-aminoquinolone acid derivatives as potent inhibitors of SARS-CoV-2

The COVID-19 pandemic caused by the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) continues to threaten human health and create socioeconomic problems worldwide. A library of 200,000 small molecules from the Korea Chemical Bank (KCB) were evaluated for their inhibitory activities agai...

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Detalles Bibliográficos
Autores principales: Shin, Young Sup, Lee, Jun Young, Jeon, Sangeun, Myung, Subeen, Gong, Hyun June, Kim, Seungtaek, Kim, Hyoung Rae, Jeong, Lak Shin, Park, Chul Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Author(s). Published by Elsevier Ltd. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9979702/
https://www.ncbi.nlm.nih.gov/pubmed/36870624
http://dx.doi.org/10.1016/j.bmcl.2023.129214