Cargando…
Discovery of 2-aminoquinolone acid derivatives as potent inhibitors of SARS-CoV-2
The COVID-19 pandemic caused by the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) continues to threaten human health and create socioeconomic problems worldwide. A library of 200,000 small molecules from the Korea Chemical Bank (KCB) were evaluated for their inhibitory activities agai...
Autores principales: | Shin, Young Sup, Lee, Jun Young, Jeon, Sangeun, Myung, Subeen, Gong, Hyun June, Kim, Seungtaek, Kim, Hyoung Rae, Jeong, Lak Shin, Park, Chul Min |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Author(s). Published by Elsevier Ltd.
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9979702/ https://www.ncbi.nlm.nih.gov/pubmed/36870624 http://dx.doi.org/10.1016/j.bmcl.2023.129214 |
Ejemplares similares
-
Optimization of 2-Aminoquinazolin-4-(3H)-one Derivatives as Potent Inhibitors of SARS-CoV-2: Improved Synthesis and Pharmacokinetic Properties
por: Shin, Young Sup, et al.
Publicado: (2022) -
Discovery of cyclic sulfonamide derivatives as potent inhibitors of SARS-CoV-2
por: Shin, Young Sup, et al.
Publicado: (2021) -
Aminoquinolones and Their Benzoquinone Dimer Hybrids as Modulators of Prion Protein Conversion
por: Costa, Amanda Rodrigues Pinto, et al.
Publicado: (2022) -
Design, synthesis and biological evaluation of 2-aminoquinazolin-4(3H)-one derivatives as potential SARS-CoV-2 and MERS-CoV treatments
por: Lee, Jun Young, et al.
Publicado: (2021) -
Synthesis and biological evaluation of 3-acyl-2-phenylamino-1,4-dihydroquinolin-4(1H)-one derivatives as potential MERS-CoV inhibitors
por: Yoon, Ji Hye, et al.
Publicado: (2019)