Tumor-independent Detection of Inherited Mismatch Repair Deficiency for the Diagnosis of Lynch Syndrome with High Specificity and Sensitivity

Lynch syndrome (LS) is the most common hereditary cancer syndrome. Early diagnosis improves prognosis and reduces health care costs, through existing cancer surveillance methods. The problem is finding and diagnosing the cancer predisposing genetic condition. The current workup involves a complex ar...

Descripción completa

Detalles Bibliográficos
Autores principales: Kansikas, Minttu, Vähätalo, Laura, Kantelinen, Jukka, Kasela, Mariann, Putula, Jaana, Døhlen, Anni, Paloviita, Pauliina, Kärkkäinen, Emmi, Lahti, Niklas, Arnez, Philippe, Kilpinen, Sami, Alcala-Repo, Beatriz, Pylvänäinen, Kirsi, Pöyhönen, Minna, Peltomäki, Päivi, Järvinen, Heikki J., Seppälä, Toni T., Renkonen-Sinisalo, Laura, Lepistö, Anna, Mecklin, Jukka-Pekka, Nyström, Minna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9979712/
https://www.ncbi.nlm.nih.gov/pubmed/36875157
http://dx.doi.org/10.1158/2767-9764.CRC-22-0384

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9979712/
https://www.ncbi.nlm.nih.gov/pubmed/36875157
http://dx.doi.org/10.1158/2767-9764.CRC-22-0384

Ejemplares similares