Impact of IDH1 and IDH2 mutation detection at diagnosis and in remission in patients with AML receiving allogeneic transplantation

Somatic mutations in the isocitrate dehydrogenase 1 and 2 genes (IDH1 and IDH2) are common in acute myeloid leukemia (AML). The prognostic impact of the presence of IDH mutations may be influenced by the comutational status, the specific location of the mutation (ie, IDH1 R132, IDH2 R140, and IDH2 R...

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Detalles Bibliográficos
Autores principales: Bill, Marius, Jentzsch, Madlen, Bischof, Lara, Kohlschmidt, Jessica, Grimm, Juliane, Schmalbrock, Laura Katharina, Backhaus, Donata, Brauer, Dominic, Goldmann, Karoline, Franke, Georg-Nikolaus, Vucinic, Vladan, Niederwieser, Dietger, Mims, Alice S., Platzbecker, Uwe, Eisfeld, Ann-Kathrin, Schwind, Sebastian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society of Hematology 2022
Materias:
Myeloid Neoplasia
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9979713/
https://www.ncbi.nlm.nih.gov/pubmed/35381077
http://dx.doi.org/10.1182/bloodadvances.2021005789

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9979713/
https://www.ncbi.nlm.nih.gov/pubmed/35381077
http://dx.doi.org/10.1182/bloodadvances.2021005789

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