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Knockdown of Stromal Interaction Molecule 1 (STIM1) Suppresses Acute Myeloblastic Leukemia-M5 Cell Line Survival Through Inhibition of Reactive Oxygen Species Activities

OBJECTIVE: This study aimed to investigate the role of the stromal interaction molecule 1 (STIM1) gene in the survival of the acute myeloblastic leukemia (AML)-M5 cell line (THP-1). MATERIALS AND METHODS: The STIM1 effect was assessed via dicer-substrate siRNA-mediated STIM1 knockdown. The effect of...

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Detalles Bibliográficos
Autores principales: Algariri, Eman Salem, Mydin, Rabiatul Basria S.M.N., Moses, Emmanuel Jairaj, Okekpa, Simon Imakwu, Rahim, Nur Arzuar Abdul, Yusoff, Narzah Mohd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Galenos Publishing 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9979743/
https://www.ncbi.nlm.nih.gov/pubmed/36404683
http://dx.doi.org/10.4274/tjh.galenos.2022.2022.0246