Elucidating parasite and host-cell factors enabling Babesia infection in sickle red cells under hypoxic/hyperoxic conditions

Sickle red blood cells (RBCs) represent a naturally existing host-cell resistance mechanism to hemoparasite infections. We investigate the basis of this resistance using Babesia divergens grown in sickle (SS) and sickle trait (AS) cells. We found that oxygenation and its corresponding effect on RBC...

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Detalles Bibliográficos
Autores principales: Beri, Divya, Singh, Manpreet, Rodriguez, Marilis, Barbu-Stevanovic, Mihaela, Rasquinha, Giselle, Mendelson, Avital, An, Xiuli, Manwani, Deepa, Yazdanbakhsh, Karina, Lobo, Cheryl A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society of Hematology 2022
Materias:
Red Cells, Iron, and Erythropoiesis
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9979759/
https://www.ncbi.nlm.nih.gov/pubmed/35977077
http://dx.doi.org/10.1182/bloodadvances.2022008159

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9979759/
https://www.ncbi.nlm.nih.gov/pubmed/35977077
http://dx.doi.org/10.1182/bloodadvances.2022008159

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