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Elucidating parasite and host-cell factors enabling Babesia infection in sickle red cells under hypoxic/hyperoxic conditions
Sickle red blood cells (RBCs) represent a naturally existing host-cell resistance mechanism to hemoparasite infections. We investigate the basis of this resistance using Babesia divergens grown in sickle (SS) and sickle trait (AS) cells. We found that oxygenation and its corresponding effect on RBC...
Autores principales: | Beri, Divya, Singh, Manpreet, Rodriguez, Marilis, Barbu-Stevanovic, Mihaela, Rasquinha, Giselle, Mendelson, Avital, An, Xiuli, Manwani, Deepa, Yazdanbakhsh, Karina, Lobo, Cheryl A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society of Hematology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9979759/ https://www.ncbi.nlm.nih.gov/pubmed/35977077 http://dx.doi.org/10.1182/bloodadvances.2022008159 |
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