Cargando…

EMD originates from hyaluronan-induced homophilic interactions of CD44 variant-expressing MM cells under shear stress

Extramedullary disease (EMD) is known to be associated with chemoresistance and poor prognosis in multiple myeloma (MM); however, the mechanisms of its development are not fully understood. Elucidating the mechanism of EMD development and its therapeutic targeting would greatly contribute to further...

Descripción completa

Detalles Bibliográficos
Autores principales: Kikuchi, Jiro, Kodama, Nobuyuki, Takeshita, Masataka, Ikeda, Sho, Kobayashi, Takahiro, Kuroda, Yoshiaki, Uchiyama, Michihiro, Osada, Naoki, Bogen, Bjarne, Yasui, Hiroshi, Takahashi, Naoto, Miwa, Akiyoshi, Furukawa, Yusuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society of Hematology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9979770/
https://www.ncbi.nlm.nih.gov/pubmed/35930695
http://dx.doi.org/10.1182/bloodadvances.2022007291