RAS and PP2A activities converge on epigenetic gene regulation

RAS-mediated human cell transformation requires inhibition of the tumor suppressor protein phosphatase 2A (PP2A). However, the phosphoprotein targets and cellular processes in which RAS and PP2A activities converge in human cancers have not been systematically analyzed. Here, we discover that phosph...

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Detalles Bibliográficos
Autores principales: Aakula, Anna, Sharma, Mukund, Tabaro, Francesco, Nätkin, Reetta, Kamila, Jesse, Honkanen, Henrik, Schapira, Matthieu, Arrowsmith, Cheryl, Nykter, Matti, Westermarck, Jukka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9979842/
https://www.ncbi.nlm.nih.gov/pubmed/36858798
http://dx.doi.org/10.26508/lsa.202301928

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9979842/
https://www.ncbi.nlm.nih.gov/pubmed/36858798
http://dx.doi.org/10.26508/lsa.202301928

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