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RAS and PP2A activities converge on epigenetic gene regulation
RAS-mediated human cell transformation requires inhibition of the tumor suppressor protein phosphatase 2A (PP2A). However, the phosphoprotein targets and cellular processes in which RAS and PP2A activities converge in human cancers have not been systematically analyzed. Here, we discover that phosph...
Autores principales: | Aakula, Anna, Sharma, Mukund, Tabaro, Francesco, Nätkin, Reetta, Kamila, Jesse, Honkanen, Henrik, Schapira, Matthieu, Arrowsmith, Cheryl, Nykter, Matti, Westermarck, Jukka |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Life Science Alliance LLC
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9979842/ https://www.ncbi.nlm.nih.gov/pubmed/36858798 http://dx.doi.org/10.26508/lsa.202301928 |
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