Characterization and decontamination of background noise in droplet-based single-cell protein expression data with DecontPro

Assays such as CITE-seq can measure the abundance of cell surface proteins on individual cells using antibody derived tags (ADTs). However, many ADTs have high levels of background noise that can obfuscate down-stream analyses. Using an exploratory analysis of PBMC datasets, we find that some drople...

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Detalles Bibliográficos
Autores principales: Yin, Yuan, Yajima, Masanao, Campbell, Joshua D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9979990/
https://www.ncbi.nlm.nih.gov/pubmed/36865227
http://dx.doi.org/10.1101/2023.01.27.525964

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9979990/
https://www.ncbi.nlm.nih.gov/pubmed/36865227
http://dx.doi.org/10.1101/2023.01.27.525964

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