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Characterization and decontamination of background noise in droplet-based single-cell protein expression data with DecontPro
Assays such as CITE-seq can measure the abundance of cell surface proteins on individual cells using antibody derived tags (ADTs). However, many ADTs have high levels of background noise that can obfuscate down-stream analyses. Using an exploratory analysis of PBMC datasets, we find that some drople...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cold Spring Harbor Laboratory
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9979990/ https://www.ncbi.nlm.nih.gov/pubmed/36865227 http://dx.doi.org/10.1101/2023.01.27.525964 |