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Cloning, characterization, and inhibition of the novel β-carbonic anhydrase from parasitic blood fluke, Schistosoma mansoni

Schistosoma mansoni is an intestinal parasite with one β-class carbonic anhydrase, SmaBCA. We report the sequence enhancing, production, catalytic activity, and inhibition results of the recombinant SmaBCA. It showed significant catalytic activity on CO(2) hydration in vitro with k(cat) 1.38 × 10(5)...

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Detalles Bibliográficos
Autores principales: Haapanen, Susanna, Angeli, Andrea, Tolvanen, Martti, Emameh, Reza Zolfaghari, Supuran, Claudiu T., Parkkila, Seppo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9980027/
https://www.ncbi.nlm.nih.gov/pubmed/36856011
http://dx.doi.org/10.1080/14756366.2023.2184299