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Cloning, characterization, and inhibition of the novel β-carbonic anhydrase from parasitic blood fluke, Schistosoma mansoni
Schistosoma mansoni is an intestinal parasite with one β-class carbonic anhydrase, SmaBCA. We report the sequence enhancing, production, catalytic activity, and inhibition results of the recombinant SmaBCA. It showed significant catalytic activity on CO(2) hydration in vitro with k(cat) 1.38 × 10(5)...
Autores principales: | Haapanen, Susanna, Angeli, Andrea, Tolvanen, Martti, Emameh, Reza Zolfaghari, Supuran, Claudiu T., Parkkila, Seppo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9980027/ https://www.ncbi.nlm.nih.gov/pubmed/36856011 http://dx.doi.org/10.1080/14756366.2023.2184299 |
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