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Cerebellar Granule Cells Develop Non-neuronal 3D Genome Architecture over the Lifespan

The cerebellum contains most of the neurons in the human brain, and exhibits unique modes of development, malformation, and aging. For example, granule cells—the most abundant neuron type—develop unusually late and exhibit unique nuclear morphology. Here, by developing our high-resolution single-cel...

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Detalles Bibliográficos
Autores principales: Tan, Longzhi, Shi, Jenny, Moghadami, Siavash, Wright, Cydney P., Parasar, Bibudha, Seo, Yunji, Vallejo, Kristen, Cobos, Inma, Duncan, Laramie, Chen, Ritchie, Deisseroth, Karl
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9980173/
https://www.ncbi.nlm.nih.gov/pubmed/36865235
http://dx.doi.org/10.1101/2023.02.25.530020