Cargando…

Atypical Chemokine Receptor 3 ‘Senses’ CXC Chemokine Receptor 4 Activation Through GPCR Kinase Phosphorylation

Atypical chemokine receptor 3 (ACKR3) is an arrestin-biased receptor that regulates extracellular chemokine levels through scavenging. The scavenging action mediates the availability of the chemokine CXCL12 for the G protein-coupled receptor (GPCR) CXCR4 and requires phosphorylation of the ACKR3 C-t...

Descripción completa

Detalles Bibliográficos
Autores principales: Schafer, Christopher T., Chen, Qiuyan, Tesmer, John J. G., Handel, Tracy M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9980177/
https://www.ncbi.nlm.nih.gov/pubmed/36865154
http://dx.doi.org/10.1101/2023.02.25.530029