Deep Learning Dynamic Allostery of G-Protein-Coupled Receptors

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G-protein-coupled receptors (GPCRs) are the largest superfamily of human membrane proteins and represent primary targets of ~ 1/3 of currently marketed drugs. Allosteric modulators have emerged as more selective drug candidates compared with orthosteric agonists and antagonists. However, many X-ray...

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Detalles Bibliográficos
Autores principales: Do, Hung, Wang, Jinan, Miao, Yinglong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9980202/
https://www.ncbi.nlm.nih.gov/pubmed/36865316
http://dx.doi.org/10.21203/rs.3.rs-2543463/v1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9980202/
https://www.ncbi.nlm.nih.gov/pubmed/36865316
http://dx.doi.org/10.21203/rs.3.rs-2543463/v1

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