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Comparison of the structure-function properties of wild-type human apoA-V and a C-terminal truncation associated with elevated plasma triglycerides

BACKGROUND: Plasma triglycerides (TGs) are causally associated with coronary artery disease and acute pancreatitis. Apolipoprotein A-V (apoA-V, gene APOA5) is a liver-secreted protein that is carried on triglyceride-rich lipoproteins and promotes the enzymatic activity of lipoprotein lipase (LPL), t...

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Detalles Bibliográficos
Autores principales: Stankov, Sylvia, Vitali, Cecilia, Park, Joseph, Nguyen, David, Mayne, Leland, Englander, S. Walter, Levin, Michael G., Vujkovic, Marijana, Hand, Nicholas J., Phillips, Michael C., Rader, Daniel J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9980232/
https://www.ncbi.nlm.nih.gov/pubmed/36865344
http://dx.doi.org/10.1101/2023.02.21.23286268