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Glioma genetic profiles associated with electrophysiologic hyperexcitability

Distinct genetic alterations determine glioma aggressiveness, however the diversity of somatic mutations contributing to peritumoral hyperexcitability and seizures is uncertain. In a large cohort of patients with sequenced gliomas (n=1716), we used discriminant analysis models to identify somatic mu...

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Detalles Bibliográficos
Autores principales: Tobochnik, Steven, Dorotan, Maria Kristina C., Ghosh, Hia S., Lapinskas, Emily, Vogelzang, Jayne, Reardon, David A., Ligon, Keith L., Bi, Wenya Linda, Smirnakis, Stelios M., Lee, Jong Woo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9980233/
https://www.ncbi.nlm.nih.gov/pubmed/36865325
http://dx.doi.org/10.1101/2023.02.22.23285841