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Genetic variation supports a causal role for valproate in prevention of ischemic stroke

Valproate is a candidate for ischemic stroke prevention due to its anti-atherosclerotic effects in vivo. Although valproate use is associated with decreased ischemic stroke risk in observational studies, confounding by indication precludes causal conclusions. To overcome this limitation, we applied...

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Detalles Bibliográficos
Autores principales: Mayerhofer, Ernst, Parodi, Livia, Narasimhalu, Kaavya, Wolking, Stefan, Harloff, Andreas, Georgakis, Marios K, Rosand, Jonathan, Anderson, Christopher D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9980256/
https://www.ncbi.nlm.nih.gov/pubmed/36865155
http://dx.doi.org/10.1101/2023.02.14.23285856