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Hippocampal Synaptic Alterations Associated with Tau Pathology in Primary Age-Related Tauopathy

Primary Age-Related Tauopathy (PART) is characterized by the aggregation of tau in the mesial temporal lobe in older individuals. High pathologic tau stage (Braak stage) or a high burden of hippocampal tau pathology have been associated with cognitive impairment in PART. However, the underlying mech...

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Detalles Bibliográficos
Autores principales: Morris, Meaghan, Coste, Gabrielle I, Redding-Ochoa, Javier, Guo, Haidan, Graves, Austin R, Troncoso, Juan C, Huganir, Richard L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9980270/
https://www.ncbi.nlm.nih.gov/pubmed/36865237
http://dx.doi.org/10.1101/2023.02.22.23286323