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Hippocampal Synaptic Alterations Associated with Tau Pathology in Primary Age-Related Tauopathy
Primary Age-Related Tauopathy (PART) is characterized by the aggregation of tau in the mesial temporal lobe in older individuals. High pathologic tau stage (Braak stage) or a high burden of hippocampal tau pathology have been associated with cognitive impairment in PART. However, the underlying mech...
Autores principales: | Morris, Meaghan, Coste, Gabrielle I, Redding-Ochoa, Javier, Guo, Haidan, Graves, Austin R, Troncoso, Juan C, Huganir, Richard L |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9980270/ https://www.ncbi.nlm.nih.gov/pubmed/36865237 http://dx.doi.org/10.1101/2023.02.22.23286323 |
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