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Adaptor proteins mediate CXCR4 and PI4KA crosstalk in prostate cancer cells and the significance of PI4KA in bone tumor growth

The chemokine receptor, CXCR4 signaling regulates cell growth, invasion, and metastasis to the bone-marrow niche in prostate cancer (PCa). Previously, we established that CXCR4 interacts with phosphatidylinositol 4-kinase IIIα (PI4KIIIα encoded by PI4KA) through its adaptor proteins and PI4KA overex...

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Detalles Bibliográficos
Autores principales: Govindarajan, Barani, Sbrissa, Diego, Pressprich, Mark, Kim, Seongho, Vaishampayan, Ulka, Cher, Michael L., Chinni, Sreenivasa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9980273/
https://www.ncbi.nlm.nih.gov/pubmed/36865146
http://dx.doi.org/10.21203/rs.3.rs-2590830/v1