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Tenascin-C activation of lung fibroblasts in a 3D synthetic lung extracellular matrix mimic

The lung extracellular matrix (ECM) maintains the structural integrity of the tissue and regulates the phenotype and functions of resident fibroblasts. Lung-metastatic breast cancer alters these cell-ECM interactions, promoting fibroblast activation. There is a need for bio-instructive ECM models th...

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Detalles Bibliográficos
Autores principales: Kundu, Aritra Nath, Dougan, Carey E., Mahmoud, Samar, Kilic, Alara, Panagiotou, Alexi, Irakoze, Ninette, Richbourg, Nathan, Peyton, Shelly R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9980292/
https://www.ncbi.nlm.nih.gov/pubmed/36865293
http://dx.doi.org/10.1101/2023.02.24.529926