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Tenascin-C activation of lung fibroblasts in a 3D synthetic lung extracellular matrix mimic
The lung extracellular matrix (ECM) maintains the structural integrity of the tissue and regulates the phenotype and functions of resident fibroblasts. Lung-metastatic breast cancer alters these cell-ECM interactions, promoting fibroblast activation. There is a need for bio-instructive ECM models th...
Autores principales: | Kundu, Aritra Nath, Dougan, Carey E., Mahmoud, Samar, Kilic, Alara, Panagiotou, Alexi, Irakoze, Ninette, Richbourg, Nathan, Peyton, Shelly R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9980292/ https://www.ncbi.nlm.nih.gov/pubmed/36865293 http://dx.doi.org/10.1101/2023.02.24.529926 |
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