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Immunoproteasome subunit β5i promotes perifascicular muscle atrophy in dermatomyositis by upregulating RIG-I

BACKGROUND: Perifascicular atrophy is a unique pathological hallmark in dermatomyositis (DM)-affected muscles; however, the mechanism underlying this process remains unclear. In this study, we aimed to investigate the potential role of the immunoproteasome subunit β5i and retinoic acid-inducible gen...

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Detalles Bibliográficos
Autores principales: Zhang, Lu, Xia, Qisheng, Li, Wenli, Liu, Qingyan, Zhang, Lining, Tian, Xiaolan, Ye, Lifang, Wang, Guochun, Peng, Qinglin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9980316/
https://www.ncbi.nlm.nih.gov/pubmed/36854567
http://dx.doi.org/10.1136/rmdopen-2022-002818