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Molecular features and predictive models identify the most lethal subtype and a therapeutic target for osteosarcoma

BACKGROUND: Osteosarcoma is the most common primary malignant bone tumor. The existing treatment regimens remained essentially unchanged over the past 30 years; hence the prognosis has plateaued at a poor level. Precise and personalized therapy is yet to be exploited. METHODS: One discovery cohort (...

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Detalles Bibliográficos
Autores principales: Zheng, Kun, Hou, Yushan, Zhang, Yiming, Wang, Fei, Sun, Aihua, Yang, Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9980341/
https://www.ncbi.nlm.nih.gov/pubmed/36874110
http://dx.doi.org/10.3389/fonc.2023.1111570