Spatial multi-omics revealed the impact of tumor ecosystem heterogeneity on immunotherapy efficacy in patients with advanced non-small cell lung cancer treated with bispecific antibody

BACKGROUND: Immunotherapy for malignant tumors has made great progress, but many patients do not benefit from it. The complex intratumoral heterogeneity (ITH) hindered the in-depth exploration of immunotherapy. Conventional bulk sequencing has masked intratumor complexity, preventing a more detailed...

Descripción completa

Detalles Bibliográficos
Autores principales: Song, Xinyu, Xiong, Anwen, Wu, Fengying, Li, Xuefei, Wang, Jing, Jiang, Tao, Chen, Peixin, Zhang, Xiaoshen, Zhao, Zhikai, Liu, Huifang, Cheng, Lei, Zhao, Chao, Wang, Zhehai, Pan, Chaohu, Cui, Xiaoli, Xu, Ting, Luo, Haitao, Zhou, Caicun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2023
Materias:
Clinical/Translational Cancer Immunotherapy
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9980352/
https://www.ncbi.nlm.nih.gov/pubmed/36854570
http://dx.doi.org/10.1136/jitc-2022-006234

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9980352/
https://www.ncbi.nlm.nih.gov/pubmed/36854570
http://dx.doi.org/10.1136/jitc-2022-006234

Ejemplares similares