Genetic evidence of aberrant striatal synaptic maturation and secretory pathway alteration in a dystonia mouse model

Animal models of DYT-TOR1A dystonia consistently demonstrate abnormalities of striatal cholinergic function, but the molecular pathways underlying this pathophysiology are unclear. To probe these molecular pathways in a genetic model of DYT-TOR1A, we performed laser microdissection in juvenile mice...

Descripción completa

Detalles Bibliográficos
Autores principales: Yellajoshyula, Dhananjay, Opeyemi, Sunday, Dauer, William T., Pappas, Samuel S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9980434/
https://www.ncbi.nlm.nih.gov/pubmed/36874764
http://dx.doi.org/10.3389/dyst.2022.10892

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9980434/
https://www.ncbi.nlm.nih.gov/pubmed/36874764
http://dx.doi.org/10.3389/dyst.2022.10892

Ejemplares similares