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Genetic evidence of aberrant striatal synaptic maturation and secretory pathway alteration in a dystonia mouse model

Animal models of DYT-TOR1A dystonia consistently demonstrate abnormalities of striatal cholinergic function, but the molecular pathways underlying this pathophysiology are unclear. To probe these molecular pathways in a genetic model of DYT-TOR1A, we performed laser microdissection in juvenile mice...

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Detalles Bibliográficos
Autores principales:	Yellajoshyula, Dhananjay, Opeyemi, Sunday, Dauer, William T., Pappas, Samuel S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9980434/ https://www.ncbi.nlm.nih.gov/pubmed/36874764 http://dx.doi.org/10.3389/dyst.2022.10892

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