Analysis of RBP expression and binding sites identifies PTBP1 as a regulator of CD19 expression in B-ALL

Despite massive improvements in the treatment of B-ALL through CART-19 immunotherapy, a large number of patients suffer a relapse due to loss of the targeted epitope. Mutations in the CD19 locus and aberrant splicing events are known to account for the absence of surface antigen. However, early mole...

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Detalles Bibliográficos
Autores principales: Ziegler, Nicole, Cortés-López, Mariela, Alt, Francesca, Sprang, Maximilian, Ustjanzew, Arsenij, Lehmann, Nadine, El Malki, Khalifa, Wingerter, Arthur, Russo, Alexandra, Beck, Olaf, Attig, Sebastian, Roth, Lea, König, Julian, Paret, Claudia, Faber, Jörg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9980455/
https://www.ncbi.nlm.nih.gov/pubmed/36875548
http://dx.doi.org/10.1080/2162402X.2023.2184143

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9980455/
https://www.ncbi.nlm.nih.gov/pubmed/36875548
http://dx.doi.org/10.1080/2162402X.2023.2184143

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