Characterization of high-molecular weight by-products in the production of a trivalent bispecific 2+1 heterodimeric antibody

The development of increasingly complex antibody formats, such as bispecifics, can lead to the formation of increasingly complex high- and low-molecular-weight by-products. Here, we focus on the characterization of high molecular weight species (HMWs) representing the highest complexity of size vari...

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Detalles Bibliográficos
Autores principales: Cramer, Dario A. T., Franc, Vojtech, Heidenreich, Anna-Katharina, Hook, Michaela, Adibzadeh, Mahdi, Reusch, Dietmar, Heck, Albert J. R., Haberger, Markus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9980510/
https://www.ncbi.nlm.nih.gov/pubmed/36799476
http://dx.doi.org/10.1080/19420862.2023.2175312

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9980510/
https://www.ncbi.nlm.nih.gov/pubmed/36799476
http://dx.doi.org/10.1080/19420862.2023.2175312

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