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Characterization of high-molecular weight by-products in the production of a trivalent bispecific 2+1 heterodimeric antibody
The development of increasingly complex antibody formats, such as bispecifics, can lead to the formation of increasingly complex high- and low-molecular-weight by-products. Here, we focus on the characterization of high molecular weight species (HMWs) representing the highest complexity of size vari...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Taylor & Francis
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9980510/ https://www.ncbi.nlm.nih.gov/pubmed/36799476 http://dx.doi.org/10.1080/19420862.2023.2175312 |