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Strategies for clinical dose optimization of T cell-engaging therapies in oncology

Innovative approaches in the design of T cell-engaging (TCE) molecules are ushering in a new wave of promising immunotherapies for the treatment of cancer. Their mechanism of action, which generates an in trans interaction to create a synthetic immune synapse, leads to complex and interconnected rel...

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Detalles Bibliográficos
Autores principales: Ball, Kathryn, Dovedi, Simon J, Vajjah, Pavan, Phipps, Alex
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9980545/
https://www.ncbi.nlm.nih.gov/pubmed/36823042
http://dx.doi.org/10.1080/19420862.2023.2181016