SDC1-dependent TGM2 determines radiosensitivity in glioblastoma by coordinating EPG5-mediated fusion of autophagosomes with lysosomes

Glioblastoma multiforme (GBM) is the most common brain malignancy insensitive to radiotherapy (RT). Although macroautophagy/autophagy was reported to be a fundamental factor prolonging the survival of tumors under radiotherapeutic stress, the autophagic biomarkers coordinated to radioresistance of G...

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Detalles Bibliográficos
Autores principales: Zheng, Wang, Chen, Qianping, Liu, Hongxia, Zeng, Liang, Zhou, Yuchuan, Liu, Xinglong, Bai, Yang, Zhang, Jianghong, Pan, Yan, Shao, Chunlin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9980589/
https://www.ncbi.nlm.nih.gov/pubmed/35913916
http://dx.doi.org/10.1080/15548627.2022.2105562

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9980589/
https://www.ncbi.nlm.nih.gov/pubmed/35913916
http://dx.doi.org/10.1080/15548627.2022.2105562

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