The Role of Gasdermin-D-Mediated Pryoptosis in Organ Injury and Its Therapeutic Implications

Gasdermin-D (GSDMD) belongs to the Gasdermin family (GSDM), which are pore-forming effector proteins that facilitate inflammatory cell death, also known as pyroptosis. This type of programmed cell death is dependent on inflammatory caspase activation, which cleaves gasdermin-D (GSDMD) to form membra...

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Detalles Bibliográficos
Autores principales: Mulla, Joud, Katti, Rohan, Scott, Melanie J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9980590/
https://www.ncbi.nlm.nih.gov/pubmed/36967609
http://dx.doi.org/10.1080/15476278.2023.2177484

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9980590/
https://www.ncbi.nlm.nih.gov/pubmed/36967609
http://dx.doi.org/10.1080/15476278.2023.2177484

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