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The Role of Gasdermin-D-Mediated Pryoptosis in Organ Injury and Its Therapeutic Implications
Gasdermin-D (GSDMD) belongs to the Gasdermin family (GSDM), which are pore-forming effector proteins that facilitate inflammatory cell death, also known as pyroptosis. This type of programmed cell death is dependent on inflammatory caspase activation, which cleaves gasdermin-D (GSDMD) to form membra...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Taylor & Francis
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9980590/ https://www.ncbi.nlm.nih.gov/pubmed/36967609 http://dx.doi.org/10.1080/15476278.2023.2177484 |