Deciphering cross-species reactivity of LAMP-1 antibodies using deep mutational epitope mapping and AlphaFold

Delineating the precise regions on an antigen that are targeted by antibodies has become a key step for the development of antibody therapeutics. X-ray crystallography and cryogenic electron microscopy are considered the gold standard for providing precise information about these binding sites at at...

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Detalles Bibliográficos
Autores principales: Pruvost, Tiphanie, Mathieu, Magali, Dubois, Steven, Maillère, Bernard, Vigne, Emmanuelle, Nozach, Hervé
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9980635/
https://www.ncbi.nlm.nih.gov/pubmed/36797224
http://dx.doi.org/10.1080/19420862.2023.2175311

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9980635/
https://www.ncbi.nlm.nih.gov/pubmed/36797224
http://dx.doi.org/10.1080/19420862.2023.2175311

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