Targeted epigenetic silencing of UCHL1 expression suppresses collagen-1 production in human lung epithelial cells

Ubiquitin carboxyl-terminal hydrolase L1 (UCHL1) is highly expressed in smokers, but little is known about the molecular mechanism of UCHL1 in airway epithelium and its possible role in affecting extracellular matrix (ECM) remodelling in the underlying submucosa. Since cigarette smoking is a major c...

Descripción completa

Detalles Bibliográficos
Autores principales: Wu, Dan-Dan, Lau, Andy T. Y., Xu, Yan-Ming, Reinders-Luinge, Marjan, Koncz, Mihaly, Kiss, Antal, Timens, Wim, Rots, Marianne G., Hylkema, Machteld N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9980648/
https://www.ncbi.nlm.nih.gov/pubmed/38016026
http://dx.doi.org/10.1080/15592294.2023.2175522

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9980648/
https://www.ncbi.nlm.nih.gov/pubmed/38016026
http://dx.doi.org/10.1080/15592294.2023.2175522

Ejemplares similares