Uncertainty quantification of reference-based cellular deconvolution algorithms

The majority of epigenetic epidemiology studies to date have generated genome-wide profiles from bulk tissues (e.g., whole blood) however these are vulnerable to confounding from variation in cellular composition. Proxies for cellular composition can be mathematically derived from the bulk tissue pr...

Descripción completa

Detalles Bibliográficos
Autores principales: Vellame, Dorothea Seiler, Shireby, Gemma, MacCalman, Ailsa, Dempster, Emma L, Burrage, Joe, Gorrie-Stone, Tyler, Schalkwyk, Leonard S, Mill, Jonathan, Hannon, Eilis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9980651/
https://www.ncbi.nlm.nih.gov/pubmed/36539387
http://dx.doi.org/10.1080/15592294.2022.2137659

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9980651/
https://www.ncbi.nlm.nih.gov/pubmed/36539387
http://dx.doi.org/10.1080/15592294.2022.2137659

Ejemplares similares