Increased SORBS3 expression in brain ageing contributes to autophagic decline via YAP1-WWTR1/TAZ signaling

Impaired autophagosome formation and reduced flux through the macroautophagy/autophagy pathway occurs outside the brain as part of normal aging in various species. We recently identified autophagic decline in mouse brain tissue dependent on aging. This sits alongside significantly increased expressi...

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Detalles Bibliográficos
Autores principales: Park, So Jung, Frake, Rebecca A., Rubinsztein, David C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9980698/
https://www.ncbi.nlm.nih.gov/pubmed/35822241
http://dx.doi.org/10.1080/15548627.2022.2100106

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9980698/
https://www.ncbi.nlm.nih.gov/pubmed/35822241
http://dx.doi.org/10.1080/15548627.2022.2100106

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